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K. Dilip Shurpali, Singh, U., Sarkar, S. Akhtar Sam, Mishra, A., Kulkarni, R., Joshi, S. P., and Sarkar, D., Advanced cell-based high-throughput screening assays targeting active and latent Mycobacterium tuberculosis, Journal of Biotechnology, vol. 185, p. S18, 2014.
D. D. Subhedar, Shaikh, M. H., Nagargoje, A. A., V. Akolkar, S., Bhansali, S. G., Sarkar, D., and Shingate, B. B., Amide-linked monocarbonyl curcumin analogues: efficient synthesis, antitubercular activity and molecular docking study, Polycyclic Aromatic Compounds, vol. 45, no. 5, pp. 2655-2671, 2022.
S. Akhtar, Singh, S., Kumar, S., and Sarkar, D., Analyzing different acetyl co-a metabolizing enzymes as potential drug targets against mycobacterium tuberculosis, British Microbiology Research Journal, vol. 10, no. 4, pp. 1-15, 2015.
G. S. Bhosle, Nawale, L., Yeware, A. M., Sarkar, D., and Fernandes, M., Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life, European Journal of Medicinal Chemistry, vol. 152, pp. 358-369, 2018.
S. B. Nadhe, Tawre, M. S., Agrawal, S., Chopade, B. A., Sarkar, D., and Pardesi, K., Anticancer potential of AgNPs synthesized using acinetobacter sp. and curcuma aromatica against HeLa cell lines: a comparative study, Journal of Trace Elements in Medicine and Biology, vol. 62, p. 126630, 2020.
R. R. Kulkarni, Tupe, S. G., Gample, S. P., Chandgude, M. G., Sarkar, D., Deshpande, M. V., and Joshi, S. P., Antifungal dimeric chalcone derivative kamalachalcone E from Mallotus philippinensis, Natural Product Research, vol. 28, no. 4, pp. 245-250, 2014.
R. R. Kulkarni, Shurpali, K., Puranik, V. G., Sarkar, D., and Joshi, S. P., Antimycobacterial labdane diterpenes from leucas stelligera, Journal of Natural Products, vol. 76, no. 10, pp. 1836-1841, 2013.
A. A. Chinchansure, Shamnani, N., Arkile, M. A., Sarkar, D., and Joshi, S. P., Antimycobacterium activity of coumarins from fruit pulp of aegle marmelos (L.) correa, International Journal of Basic and Applied Chemical Sciences, vol. 5, no. 3, pp. 39-44, 2015.
L. Nawale, Dubey, P., Chaudhari, B., Sarkar, D., and Prabhune, A., Anti-proliferative effect of novel primary cetyl alcohol derived sophorolipids against human cervical cancer cells HeLa, Plos One, vol. 12 , no. 4, p. e0174241, 2017.
P. Nigam, Waghmode, S. A., Yeware, A. M., Nawale, L. U., Dagde, P., Dudhane, A., and Sarkar, D., Aptamer functionalized multifunctional fluorescent nanotheranostic platform for pancreatic cancer, Journal of Nanopharm Drug Delivery, 2014.
C
N. Tiwari, Nawale, L. U., Sarkar, D., and Badiger, M. V., Carboxymethyl cellulose-grafted mesoporous silica hybrid nanogels for enhanced cellular uptake and release of curcumin, Gels, vol. 3, no. 1, 2017.
R. Singh, Nawale, L. U., Arkile, M. A., Shedbalkar, U. U., Wadhwani, S. A., Sarkar, D., and Chopade, B. Ananda, Chemical and biological metal nanoparticles as antimycobacterial agents: a comparative study, International Journal of Antimicrobial Agents, vol. 46, no. 2, pp. 183-188, 2015.
, ,, Wadgaonkar, P. P., Tapase, S. R., Kodam, K. M., Choudhari, A., and Sarkar, D., Click chemistry based multicomponent approach in the synthesis of spirochromenocarbazole tethered 1,2,3-triazoles as potential anticancer agents, Bioorganic Chemistry, vol. 85, pp. 475-486, 2019.
P. V. Chavan, Pandit, K. S., Desai, U. V., Wadgaonkar, P. P., Nawale, L., Bhansali, S., and Sarkar, D., Click-chemistry-based multicomponent condensation approach for design and synthesis of spirochromene-tethered 1,2,3-triazoles as potential antitubercular agents, Research on Chemical Intermediates, vol. 43, no. 10, pp. 5675-5690, 2017.
A. S. Kotmale, Sangtani, E., Gonnade, R. G., Sarkar, D., Burade, S., Rajamohanan, P. R., and Sanjayan, G. J., Conformational studies of Ant-Pro motif-incorporated cyclic peptides: gramicidin S and avellanin, New Journal of Chemistry, vol. 42, no. 2, pp. 1197-1201, 2018.
N. C. Desai, Bhatt, K., Jadeja, D. J., Mehta, H. K., Khedkar, V. M., and Sarkar, D., Conventional and microwave-assisted organic synthesis of novel antimycobacterial agents bearing furan and pyridine hybrids, Drug Development Research, vol. 83, no. 2, pp. 416-431, 2022.
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D. D. Subhedar, Shaikh, M. H., Nagargoje, A. A., Sarkar, D., Khedkar, V. M., and Shingate, B. B., [DBUH][OAc]-catalyzed domino synthesis of novel benzimidazole incorporated 3,5-Bis (Arylidene)-4-piperidones as potential antitubercular agents, Polycyclic Aromatic Compounds, vol. 42, no. 10, pp. 7010-7024, 2022.
V. S. Pore, Divse, J. M., Charolkar, C. R., Nawale, L. U., Khedkar, V. M., and Sarkar, D., Design and synthesis of 11 alpha-substituted bile acid derivatives as potential anti-tuberculosis agents, Bioorganic & Medicinal Chemistry Letters, vol. 25, no. 19, pp. 4185-4190, 2015.
S. B. Baravkar, Wagh, M. A., Nawale, L. U., Choudhari, A. S., Bhansali, S., Sarkar, D., and Sanjayan, G. J., Design and synthesis of 2-amino-thiophene-proline-conjugates and their anti-tubercular activity against mycobacterium tuberculosis H37Ra, ChemistrySelect, vol. 4, no. 9, pp. 2851-2857, 2019.
M. A. Wagh, Baravkar, S. B., Jedhe, G. S., Borkute, R., Choudhari, A. S., Sarkar, D., and Sanjayan, G. J., Design and synthesis of 2-amino-thiophene-tethered ureidopenicillin analogs with potentantibacterial and antitubercular activity, ChemistrySelect, vol. 3, no. 11, pp. 3122-3126, 2018.
A. C. Lele, Raju, A., Khambete, M. P., Ray, M. K., Rajan, M. G. R., Arkile, M. A., Jadhav, N. J., Sarkar, D., and Degani, M. S., Design and synthesis of a focused library of diamino triazines as potential mycobacterium tuberculosis DHFR inhibitors, ACS Medicinal Chemistry Letters, vol. 6, no. 11, pp. 1140-1144, 2015.
S. Singh, Navale, G. R., Agrawal, S., Singh, H. Kisan, Singla, L., Sarkar, D., Sarma, M., Choudhury, A. Roy, and Ghosh, K., Design and synthesis of piano-stool ruthenium(II) complexes and their studies on the inhibition of amyloid ? (1-42) peptide aggregation, International Journal of Biological Macromolecules, vol. 239, p. 124197, 2023.
A. Atmaram Upare, Gadekar, P. K., Sivaramakrishnan, H., Naik, N., Khedkar, V. M., Sarkar, D., Choudhari, A., and S. Roopan, M., Design, synthesis and biological evaluation of (E)-5-styryl-1,2,4-oxadiazoles as anti-tubercular agents, Bioorganic Chemistry, vol. 86, pp. 507-512, 2019.
P. K. Gadekar, Roychowdhury, A., Kharkar, P. S., Khedkar, V. M., Arkile, M. A., Manek, H., Sarkar, D., Sharma, R., Vijayakumar, V., and Sarveswari, S., Design, synthesis and biological evaluation of novel azaspiro analogs of linezolid as antibacterial and antitubercular agents, European Journal of Medicinal Chemistry, vol. 122, pp. 475-487, 2016.
M. S. Tambe, Choudhari, A., Sarkar, D., Sangshetti, J., Patil, R., and Gholap, S. S., Design, synthesis and biological screening of novel 1,3,4-oxadiazoles as antitubercular agents, Chemistryselect, vol. 3, no. 47, pp. 13304-13310, 2018.
R. Mamgain, Swami, S., Sarkar, D., and Srivastava, P., Design, synthesis, and in vitro biological evaluation of ROS-generating phenanthridin-trione-epoxide conjugates as agents against mycobacterium tuberculosis, ChemistrySelect, vol. 8, no. 25, p. e202300416, 2023.
S. Gholap, Tambe, M., Nawale, L., Sarkar, D., Sangshetti, J., and Damale, M., Design, synthesis, and pharmacological evaluation of fluorinated azoles as anti-tubercular agents, Archiv Der Pharmazie, vol. 351, no. 2, p. e1700294, 2018.
R. Gawali, Trivedi, J., Bhansali, S., Bhosale, R., Sarkar, D., and Mitra, D., Design, synthesis, docking studies and biological screening of 2-thiazolyl substituted-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines as potent HIV-1 reverse transcriptase inhibitors, European Journal of Medicinal Chemistry, vol. 157, pp. 310-319, 2018.
S. Sarkar, Swami, S., Soni, S. Kumar, Holien, J. K., Khan, A., Korwar, A. M., Likhite, A. P., Joshi, R. A., Joshi, R. R., and Sarkar, D., Detection of a target protein (GroEl2) in Mycobacterium tuberculosis using a derivative of 1,2,4-triazolethiols, Molecular Diversity, vol. 26, no. 5, pp. 2535-2548, 2022.
U. Singh, Panchanadikar, V., and Sarkar, D., Development of a simple assay protocol for high-throughput screening of mycobacterium tuberculosis glutamine synthetase for the identification of novel inhibitors, Journal of Biomolecular Screening, vol. 10, no. 7, pp. 725-729, 2005.
U. Singh and Sarkar, D., Development of a simple high-throughput screening protocol based on biosynthetic activity of Mycobacterium tuberculosis glutamine synthetase for the identification of novel inhibitors, Journal of Biomolecular Screening, vol. 11, no. 8, pp. 1035-1042, 2006.
L. Nawale and Sarkar, D., Discovery of new chemical entities against diseases of national importance :an HTS approach, in National Science Day, At CSIR-NCL, Combi Chem-Bio Resource Center, OCD, National Chemical Laboratory, Pune - 411 008, 2015.
G. Navale, Singh, S., Agrawal, S., Ghosh, C., Choudhury, A. Roy, Roy, P., Sarkar, D., and Ghosh, K., DNA binding, antitubercular, antibacterial and anticancer studies of newly designed piano-stool ruthenium(ii) complexes, Dalton Transactions, vol. 51, no. 42, pp. 16371-16382, 2022.
H
A. Yeware, Agrawal, S., and Sarkar, D., High content screening assay for identifying inhibitors against active and dormant state intracellular Mycobacterium tuberculosis, Journal of Microbiological Methods, vol. 164, 2019.
H. Manek, Nawale, L., Jadhav, N. J., and Sarkar, D., High throughput screening of inhibitors for tuberculosis at NCL : a novel drug discovery initiative from CSIR, in 73rd CSIR Foundation Day, at CSIR-National Chemical Laboratory, Pune, CSIR-National Chemical Laboratory, Pune, 2015.
S. Abdul Rash Mulla, Pathan, M. Y., Chavan, S. S., Gample, S. P., and Sarkar, D., Highly efficient one-pot multi-component synthesis of alpha-aminophosphonates and bis-alpha-aminophosphonates catalyzed by heterogeneous reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) at ambient temperature and their antitubercular eval, RSC Advances, vol. 4, no. 15, pp. 7666-7672, 2014.
J. Bhat, Rane, R., Solapure, S. M., Sarkar, D., Sharma, U., Harish, M. N., Lamb, S., Plant, D., Alcock, P., Peters, S., Barde, S., and Roy, R. K., High-throughput screening of RNA polymerase inhibitors using a fluorescent UTP analog, Journal of Biomolecular Screening, vol. 11, no. 8, pp. 968-976, 2006.
M. M. Pisal, Nawale, L. U., Patil, M., Bhansali, S. G., Gajbhiye, J. M., Sarkar, D., Chavan, S. P., and Borate, H. B., Hybrids of thienopyrimidinones and thiouracils as anti-tubercular agents: SAR and docking studies, European Journal of Medicinal Chemistry, vol. 127, 2017.
I
A. Khan and Sarkar, D., Identification of a respiratory-type nitrate reductase and its role for survival of mycobacterium smegmatis in wayne model, Microbial Pathogenesis, vol. 41, no. 2-3, pp. 90-95, 2006.
T. S. Chitre, Asgaonkar, K. D., Vikhe, A. B., Patil, S. M., Garud, D. R., Khedkar, V. M., Sarkar, D., Nawale, L. U., and Yeware, A., In silico studies, synthesis and antitubercular activity of some novel quinoline - azitidinone derivatives, Current Computer-Aided Drug Design, vol. 17, no. 1, pp. 134-143, 2021.
V. S. Honmore, Rojatkar, S. R., Nawale, L. U., Arkile, M. A., Khedkar, V. M., Natu, A. D., and Sarkar, D., In vitro and ex vivo antitubercular activity of diarylheptanoids from the rhizomes of alpinia officinarum hance, Natural Product Research, vol. 30, no. 24, pp. 2825-2830, 2016.
V. Honmore, Kalyankar, V., Natu, A., Khedkar, V., Sarkar, D., and Rojatkar, S., In vitro antitubercular screening and in silico study of germacradienolide from blainvillea latifolia, Asian Journal of Chemistry, vol. 33, no. 12, pp. 3129-3133, 2021.
R. Saini, Navale, G. R., Singh, S., Singh, H. Kisan, Chauhan, R., Agrawal, S., Sarkar, D., Sarma, M., and Ghosh, K., Inhibition of amyloid β1-42 peptide aggregation by newly designed cyclometallated palladium complexes, International Journal of Biological Macromolecules, vol. 248, p. 125847, 2023.
S. K. Soni, Sarkar, S., Selvakannan, P. R., Sarkar, D., and Bhargava, S. Kumar, Intrinsic therapeutic and biocatalytic roles of ionic liquid mediated self-assembled platinum-phytase nanospheres, RSC Advances, vol. 5, no. 77, pp. 62871-62881, 2015.
V. S. Honmore, Kandhare, A. D., Kadam, P. P., Khedkar, V. M., Sarkar, D., Bodhankar, S. L., Zanwar, A. A., Rojatkar, S. R., and Natu, A. D., Isolates of alpinia officinarum hance as COX-2 inhibitors: evidence from anti-inflammatory, antioxidant and molecular docking studies, International Immunopharmacology, vol. 33, pp. 8-17, 2016.
M
P. Dubey, Nawale, L., Sarkar, D., Nisal, A., and Prabhune, A., Mechanistic understanding of rapid gelation of silk fibroin using a biosurfactant – sophorolipid, in National Science Day, At CSIR-NCL, National Chemical Laboratory, Pune India, 2015.
S. Akhtar, Sarkar, S., Mishra, A., and Sarkar, D., Method to extract intact and pure RNA from mycobacteria, Analytical Biochemistry, vol. 417, no. 2, pp. 286-288, 2011.
N. V. Puranik, Srivastava, P., Swami, S., Choudhari, A., and Sarkar, D., Molecular modeling studies and in vitro screening of dihydrorugosaflavonoid and its derivatives against mycobacterium tuberculosis, RSC Advances, vol. 8, no. 19, pp. 10634-10643, 2018.
P. Nigam Joshi, Agawane, S., Agawane, S., Agawane, S., Sarkar, D., and Sarkar, D., Multifunctional inulin tethered silver-graphene quantum dots nanotheranostic module for pancreatic cancer therapy, Material Science and Engineering C- Materials for Biological Application, vol. 78, 2017.
P. Nigam Joshi, Agawane, S., Agawane, S., Agawane, S., Sarkar, D., and Sarkar, D., Multifunctional inulin tethered silver-graphene quantum dots nanotheranostic module for pancreatic cancer therapy, Material Science and Engineering C- Materials for Biological Application, vol. 78, 2017.
P. Nigam and Sarkar, D., Multifunctional silica nanoparticles for pancreatic cancer specific drug delivery and bioimaging, Journal of Chemistry & Applied Biochemistry, vol. 2, no. 1, 2015.
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T. R. Valkute, Arkile, M. A., Sarkar, D., and Bhattacharya, A. K., Naturally occurring anti-TB agents: isolation, chemical transformations and in vitro antitubercular activities of secondary metabolites of rhizomes of alpinia galanga, Planta Medica International Open, vol. 3, no. 3, pp. e55-e59, 2016.
M. B. Bhalerao, Dhumal, S. T., Deshmukh, A. R., Nawale, L. U., Khedkar, V. M., Sarkar, D., and Mane, R. A., New bithiazolyl hydrazones: novel synthesis, characterization and antitubercular evaluation, Bioorganic & Medicinal Chemistry Letters, vol. 27, no. 2, pp. 288–294, 2017.
M. S. Said, Chinchansure, A. A., Nawale, L., Durge, A., Wadhwani, A., Kulkarni, S. S., Sarkar, D., and Joshi, S. P., New butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum, Natural Product Research, vol. 29, no. 22, pp. 2080-2086, 2015.
A. A. Chinchansure, Arkile, M. A., Shinde, D. R., Sarkar, D., and Joshi, S. P., New dinor-cis-labdane diterpene and flavonoids with antimycobacterium activity from colebrookea oppositifolia, Planta Medica Letters, vol. 3, no. 1, pp. e20-e24, 2016.
R. R. Kulkarni, Shurpali, K., Khedkar, V. M., Puranik, V. G., Sarkar, D., and Joshi, S. P., New pimarane diterpenes and other antimycobacterial metabolites from anisochilus verticillatus, Natural Product Research, vol. 30, no. 6, pp. 675-681, 2016.
A. Khan and Sarkar, D., Nitrate reduction pathways in mycobacteria and their implications during latency, Microbiology-SGM, vol. 158, pp. 301-307, 2012.
S. Akhtar, Khan, A., Sohaskey, C. D., Jagannath, C., and Sarkar, D., Nitrite reductase NirBD is induced and plays an important role during in vitro dormancy of mycobacterium tuberculosis, Journal of Bacteriology, vol. 195, no. 20, pp. 4592-4599, 2013.
T. S. Chitre, Patil, S. M., Sujalegaonkar, A. G., Asgaonkar, K. D., Khedkar, V. M., Garud, D. R., Jha, P. C., Gaikwad, S. Y., Kulkarni, S., Choudhari, A., and Sarkar, D., Non nucleoside reverse transcriptase inhibitors, molecular docking studies and antitubercular activity of thiazolidin-4-one derivatives, Current Computer-Aided Drug Design, vol. 15, no. 5, pp. 433-444, 2019.
M. H. Shaikh, Subhedar, D., Nawale, L., Sarkar, D., Khan, F. A. Kalam, Sangshetti, J., and Shingate, B. B., Novel benzylidenehydrazide-1,2,3-triazole conjugates as antitubercular agents: synthesis and molecular docking, Mini Reviews in Medicinal Chemistry, vol. 18, 2018.
S. Agrawal, Gample, S., Yeware, A., and Sarkar, D., Novel gene similar to nitrite reductase (NO forming) plays potentially important role in the latency of tuberculosis, Scientific Reports, vol. 11, no. 1, p. 19813, 2021.
A. Yeware and Sarkar, D., Novel red fluorescence protein based microplate assay for drug screening against dormant mycobacterium tuberculosis by using paraffin, Tuberculosis, vol. 110, pp. 15-19, 2018.
U. Singh, Akhtar, S., Mishra, A., and Sarkar, D., Novel screening method based on menadione mediated rapid reduction of tetrazolium salt for testing of anti-mycobacterial agents, Journal of Microbiological Methods, vol. 84, no. 2, pp. 202-207, 2011.
D. D. Subhedar, Shaikh, M. H., Nawale, L., Yeware, A., Sarkar, D., Khan, F. A. Kalam, Sangshetti, J. N., and Shingate, B. B., Novel tetrazoloquinoline-rhodanine conjugates: highly efficient synthesis and biological evaluation, Bioorganic & Medicinal Chemistry Letters, vol. 26, no. 9, pp. 2278-2283, 2016.
D. D. Subhedar, Shaikh, M. H., Shingate, B. B., Nawale, L., Sarkar, D., and Khedkar, V. M., Novel tetrazoloquinoline-thiazolidinone conjugates as possible antitubercular agents: synthesis and molecular docking, Medchemcomm, vol. 7, no. 9, pp. 1832-1848, 2016.
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R. Balasaheb Aher and Sarkar, D., Pharmacophore modeling of pretomanid (PA-824) derivatives for antitubercular potency against replicating and non-replicating Mycobacterium tuberculosis, Journal of Biomolecular Structure & Dynamics, vol. 39, no. 3, pp. 889-900, 2021.
R. R. Kulkarni, Shurpali, K., Gawade, R. L., Sarkar, D., Puranik, V. G., and Joshi, S. P., Phyllocladane diterpenes from anisomeles heyneana, Journal of Asian Natural Products Research, vol. 14, no. 12, pp. 1162-1168, 2012.
R. Singh, Nawale, L., Arkile, M. A., Wadhwani, S., Shedbalkar, U., Chopade, S., Sarkar, D., and Chopade, B. Ananda, Phytogenic silver, gold, and bimetallic nanoparticles as novel antitubercular agents, International Journal of Nanomedicine, vol. 11, p. 1889—1897, 2016.
S. Sarkar and Sarkar, D., Potential use of nitrate reductase as a biomarker for the identification of active and dormant inhibitors of mycobacterium tuberculosis in a THP1 infection model, Journal of Biomolecular Screening, vol. 17, no. 7, pp. 966-973, 2012.
A. Khan, Akhtar, S., Ahmad, J. N., and Sarkar, D., Presence of a functional nitrate assimilation pathway in mycobacterium smegmatis, Microbial Pathogenesis, vol. 44, no. 1, pp. 71-77, 2008.
A. Yeware, Akhtar, S., and Sarkar, D., Probes and techniques used in active and the hypoxia-based dormant state of an antitubercular drug screening assay, Medicine in Drug Discovery, vol. 13, p. 100115, 2022.
D. Sreekanth, Syed, A., Sarkar, S., Sarkar, D., Santhakumari, B., Ahmad, A., and Khan, M. Islam, Production, purification, and characterization of taxol and 10-DABIII from a new endophytic fungus gliocladium sp isolated from the Indian yew tree, taxus baccata, Journal of Microbiology and Biotechnology, vol. 19, no. 11, pp. 1342-1347, 2009.
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S. Kumar Soni, Sarkar, S., Sarkar, D., Coloe, P. J., Bhargava, S. Kumar, and Bansal, V., Self–assembled histidine acid phosphate nanocapsules as templates for multifunctional hollow platinum nanospheres in ionic liquid [BMIM][BF 4 ] for drug delivery, Proceedings of Chemeca. 2012.
P. R. Sharma, Kamble, S., Sarkar, D., Anand, A., and Varma, A., Shape and size engineered cellulosic nanomaterials as broad spectrum anti-microbial compounds, International Journal of Biological Macromolecules, vol. 87, pp. 460-465, 2016.
A. Khan and Sarkar, D., Simple whole cell based high throughput screening protocol using Mycobacterium bovis BCG for inhibitors against dormant and active tubercle bacilli, Journal of Microbiological Methods, vol. 73, no. 1, pp. 62-68, 2008.
P. Dubey, Nawale, L., Sarkar, D., Nisal, A., and Prabhune, A., Sophorolipid assisted tunable and rapid gelation of silk fibroin to form porous biomedical scaffolds, RSC Advances, vol. 5, no. 43, pp. 33955-33962, 2015.
A. M. Yeware, Shurpali, K. D., Athalye, M. C., and Sarkar, D., Superoxide generation and its involvement in the growth of mycobacterium smegmatis, Frontiers in Microbiology, vol. 8, p. Article Number: 105, 2017.
V. Shinde, Mahulikar, P., Mhaske, P. C., Chakraborty, S., Choudhari, A., Phalle, S., Choudhari, P., and Sarkar, D., Synthesis and antimycobacterial evaluation of new 5-(1-benzyl-1H-1,2,3-triazol-4-yl)-4-methyl-2-arylthiazole derivatives, Medicinal Chemistry Research, vol. 28, no. 6, pp. 805-819, 2019.

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