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Conference Paper
V. Maralingannavar, Parmar, D., Pant, T., Gadgil, C., Panchagnula, V., and Gadgil, M., “Differential responses of CHO cells adapted to limitation of inorganic phosphate, glucose or glutamine”, in 255th National Meeting and Exposition of the American-Chemical-Society (ACS) - Nexus of Food, Energy, and Water, New Orleans, LA, 2018.
Journal Article
J. Rawat, Bhambri, A., Pandey, U., Banerjee, S., Pillai, B., and Gadgil, M., “Amino acid abundance and composition in cell culture medium affects trace metal tolerance and cholesterol synthesis”, Biotechnology Progress, vol. 39, no. 1, 2023.
M. Gadgil, Lian, W., Gadgil, C. J., Kapur, V., and Wu, W. S., “Analysis of the use of genomic DNA as a universal reference in two channel DNA microarrays”, BMC Genomics, vol. 6, p. Article Number. 66, 2005.
M. Gadgil, “Cell culture processes for biopharmaceutical manufacturing”, Current Science, vol. 112, no. 7, pp. 1478-1488, 2017.
H. Le, Vishwanathan, N., Jacob, N. M., Gadgil, M., and Hu, W. - S., “Cell line development for biomanufacturing processes: recent advances and an outlook”, Biotechnology Letters, vol. 37, no. 8, pp. 1553-1564, 2015.
V. ; Maralingannavar, Parmar, D., Pant, T., Gadgil, C., Panchagnula, V., and Gadgil, M., “CHO Cells Adapted to Inorganic Phosphate Limitation Show Higher Growth and Higher Pyruvate Carboxylase Flux in Phosphate Replete Conditions”, Biotechnology progress, vol. 33, no. 3, pp. 749-758, 2017.
V. Vijayan, Bulsara, B., Gadgil, C. J., and Gadgil, M., “Comparison of feature selection and classification combinations for cancer classification using microarray data”, International Journal of Bioinformatics Research and Applications, vol. 5, no. 4, pp. 417-431 , 2009.
V. Vijayan, Deshpande, P., Gadgil, C. J., and Gadgil, M., “Comparison of methods for identifying periodically varying genes”, International Journal of Bioinformatics Research and Applications, vol. 9, no. 1, pp. 53-70, 2013.
S. Hegde, Pant, T., Pradhan, K., Badiger, M. V., and Gadgil, M., “Controlled release of nutrients to mammalian cells cultured in shake flasks”, Biotechnology Progress, vol. 28, no. 1, pp. 188-195, 2012.
M. Gadgil, “Development of a mathematical model for animal cell culture without pH control and its application for evaluation of clone screening outcomes in shake flask culture”, Journal of Chemical Technology and Biotechnology, vol. 90, no. 1, pp. 166-175, 2015.
K. Pradhan and Gadgil, M., “Effect of addition of `carrier' DNA during transient protein expression in suspension CHO culture”, Cytotechnology, vol. 64, no. 6, pp. 613-622, 2012.
A. Prabhu, Shanmugam, D., and Gadgil, M., “Engineering nucleotide sugar synthesis pathways for independent and simultaneous modulation of N-glycan galactosylation and fucosylation in CHO cells”, Metabolic Engineering, vol. 74, pp. 61-71, 2022.
V. Maralingannavar, Shenoy, B. R., Hazarika, J., Unnikrishnan, D., Prabhu, A., Maity, S., and Gadgil, M., “ In situ base release for pH maintenance can allow shake flasks to better mimic bioreactor performance for CHO cell culture”, Journal of Chemical Technology & Biotechnology, vol. 93, no. 10, pp. 2842-2850, 2018.
K. Pradhan, Pant, T., and Gadgil, M., “In situ pH maintenance for mammalian cell cultures in shake flasks and tissue culture flasks”, Biotechnology Progress, vol. 28, no. 6, pp. 1605-1610, 2012.
R. Sanil, Maralingannavar, V., and Gadgil, M., “In situ pH management for microbial culture in shake flasks and its application to increase plasmid yield”, Journal of Industrial Microbiology & Biotechnology, vol. 41, no. 4, pp. 647-655, 2014.
S. Thombre and Gadgil, M., “Increase in efficiency of media utilization for recombinant protein production in Chinese hamster ovary culture through dilution”, Biotechnology and Applied Biochemistry, vol. 58, no. 1, pp. 25-31, 2011.
T. Surve and Gadgil, M., “Manganese increases high mannose glycoform on monoclonal antibody expressed in cho when glucose is absent or limiting: implications for use of alternate sugars”, Biotechnology Progress, vol. 31, no. 2, pp. 460-467, 2015.
A. Sreejan, Gadgil, M., and Gadgil, C. J., “Mathematical model of the multi-amino acid multi-transporter system predicts uptake flux in CHO cells”, Journal of Biotechnology, vol. 344, pp. 40-49, 2022.
M. Gadgil, “Population proportion approach for ranking differentially expressed genes”, BMC Bioinformatics, vol. 9, p. Article No. 380, 2008.
R. Roshan, Ghosh, T., Gadgil, M., and Pillai, B., “Regulation of BACE1 by miR-29a/b in a cellular model of spinocerebellar ataxia 17”, RNA Biology, vol. 9, no. 6, pp. 891-899, 2012.
J. Rawat and Gadgil, M., “Shear stress increases cytotoxicity and reduces transfection efficiency of liposomal gene delivery to CHO-S cells”, Cytotechnology, vol. 68, no. 6, pp. 2529-2538, 2016.
V. Maralingannavar, Parmar, D., Panchagnula, V., and Gadgil, M., “Superfluous glutamine synthetase activity in Chinese Hamster Ovary cells selected under glutamine limitation is growth limiting in glutamine-replete conditions and can be inhibited by serine”, Biotechnology Progress, vol. 35, no. 5, p. UNSP e2856, 2019.
J. Rawat and Gadgil, M., “Towards in situ continuous feeding via controlled release of complete nutrients for fed-batch culture of animal cells”, Biochemical Engineering Journal, vol. 154, p. 107436, 2020.
A. Prabhu and Gadgil, M., “Trace metals in cellular metabolism and their impact on recombinant protein production”, Process Biochemistry, vol. 110, pp. 251-262, 2021.
A. Nisal, Trivedy, K., Mohammad, H., Panneri, S., Gupta, S. Sen, Lele, A. K., Manchala, R., Kumar, N. S., Gadgil, M., Khandelwal, H. B., More, S., and Laxman, R. Seeta, “Uptake of Azo dyes into silk glands for production of colored silk cocoons using a green feeding approach”, ACS Sustainable Chemistry & Engineering, vol. 2, pp. 312-317, 2014.
A. Prabhu, “Zinc supplementation decreases galactosylation of recombinant IgG in CHO cells”, Applied Microbiology and Biotechnology, pp. 1-11, 2018.