01109nas a2200205 4500008004100000022001400041245006300055210006300118260000900181300001400190490000800204520048100212653002200693653002600715653000800741653001800749653002400767100001900791856009300810 2017 eng d a0011-389100aCell culture processes for biopharmaceutical manufacturing0 aCell culture processes for biopharmaceutical manufacturing cAPR a1478-14880 v1123 a
Recombinant proteins manufactured using animal cell culture processes comprise a significant fraction of biopharmaceuticals. With the expiry of patents on this class of therapeutics, there is also a significant interest in manufacture of biosimilar versions of such therapeutics. This article provides a birds-eye view of upstream process development for animal cell culture processes, with a focus on advances pertinent to the development of processes for biosimilars.
10aBiopharmaceutical10aCell line development10aCHO10aglycosylation10amonoclonal antibody1 aGadgil, Mugdha uhttp://library.ncl.res.in/content/cell-culture-processes-biopharmaceutical-manufacturing