Cell culture processes for biopharmaceutical manufacturing

TitleCell culture processes for biopharmaceutical manufacturing
Publication TypeJournal Article
Year of Publication2017
AuthorsGadgil, M
JournalCurrent Science
Volume112
Issue7
Pagination1478-1488
Date PublishedAPR
Type of ArticleArticle
ISSN0011-3891
KeywordsBiopharmaceutical, Cell line development, CHO, glycosylation, monoclonal antibody
Abstract

Recombinant proteins manufactured using animal cell culture processes comprise a significant fraction of biopharmaceuticals. With the expiry of patents on this class of therapeutics, there is also a significant interest in manufacture of biosimilar versions of such therapeutics. This article provides a birds-eye view of upstream process development for animal cell culture processes, with a focus on advances pertinent to the development of processes for biosimilars.

DOI10.18520/cs/v112/i07/1478-1488
Type of Journal (Indian or Foreign)Indian
Impact Factor (IF)0.883
Divison category: 
Chemical Engineering & Process Development

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