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Book Chapter
A. Pandit, Bhambure, R., and Ranade, V. V., “Population balance-enabled model for batch and continuous crystallization processes”, in Chemical Engineering in the Pharmaceutical Industry, John Wiley & Sons, Inc., 2019.
Conference Paper
A. Rathore and Bhambure, R., “Implementation of QbD for development of a downstream process for a therapeutic biosimilar”, in 253rd National Meeting of the American-Chemical-Society (ACS) on Advanced Materials, Technologies, Systems, and Processes, San Francisco, CA, 2017.
Journal Article
S. Rana, Ughade, S., Kumthekar, R., and Bhambure, R., “Chromatography assisted in-vitro refolding and purification of recombinant peptibody: recombinant romiplostim a case study”, International Journal of Biological Macromolecules, vol. 249, p. 126037, 2023.
D. Mehta, Chirmade, T., Tungekar, A. A., Gani, K., and Bhambure, R., “Cloning and expression of antibody fragment (Fab) I: effect of expression construct and induction strategies on light and heavy chain gene expression”, Biochemical Engineering Journal, vol. 176, p. 108189, 2021.
W. Khan, Khan, N., Mishra, A., Gupta, S., Bansode, V., Mehta, D., Bhambure, R., and Rathore, A., “Dimerization of SARS-CoV-2 nucleocapsid protein affects sensitivity of ELISA based diagnostics of COVID-19”, International Journal of Biological Macromolecules, vol. 200, pp. 428-437, 2022.
V. Amritkar, Adat, S., Tejwani, V., Rathore, A., and Bhambure, R., “Engineering staphylococcal protein A for high-throughput affinity purification of monoclonal antibodies”, Biotechnology Advances, vol. 44, p. 107632, 2020.
A. Ghosh, Pawar, A. B., Chirmade, T., Jathar, S. M., Bhambure, R., Sengupta, D., Giri, A. P., and Kulkarni, M. J., “Investigation of the captopril-insulin interaction by mass spectrometry and computational approaches reveals that captopril induces structural changes in insulin”, ACS Omega, vol. 7, no. 27, pp. 23115-23126, 2022.
R. Kumthekar, Rana, S., Ughade, S., and Bhambure, R., “Mapping time dependent disulfide bond formation during in-vitro refolding of recombinant peptibody: a Fc-fusion protein”, Biochemical Engineering Journal, vol. 197, p. 108969, 2023.
P. Deulgaonkar, Bhambure, R., Prasad, B., Mishra, A., Tiwari, S., and Mody, R., “Mechanistic modeling of continuous capture step purification of biosimilar monoclonal antibody therapeutic”, Journal of Chemical Technology and Biotechnology, vol. 97, no. 9, pp. 2404-2419, 2022.
K. Gani, Chirmade, T., Ughade, S., Thulasiram, H., and Bhambure, R., “Understanding unfolding and refolding of the antibody fragment (Fab) III: mapping covalent and non-covalent interactions during in-vitro refolding of light chain, heavy chain, and Fab.”, Biochemical Engineering Journal, vol. 187, p. 108644, 2022.
K. Gani, Bhambure, R., Deulgaonkar, P., Mehta, D., and Kamble, M., “Understanding unfolding and refolding of the antibody fragment (Fab). I. In-vitro study”, Biochemical Engineering Journal, vol. 164, p. 107764, 2020.
N. Nainwal, Chirmade, T., Gani, K., Rana, S., and Bhambure, R., “Understanding unfolding and refolding of the antibody fragments (Fab). II. Mapping intra and inter-chain disulfide bonds using mass spectrometry”, Biochemical Engineering Journal, vol. 182, p. 108439, 2022.