Catalytic asymmetric transfer hydrogenation of ketones using [Ru(p-cymene)Cl-2](2) with chiral amino alcohol ligands
| Title | Catalytic asymmetric transfer hydrogenation of ketones using [Ru(p-cymene)Cl-2](2) with chiral amino alcohol ligands |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | Deshpande, SH, Kelkar, AA, Gonnade, RG, Shingote, SK, Chaudhari, RV |
| Journal | Catalysis Letters |
| Volume | 138 |
| Issue | 3-4 |
| Pagination | 231-238 |
| Date Published | SEP |
| ISSN | 1011-372X |
| Keywords | Amino alcohol ligand, Asymmetric transfer hydrogenation, Ketones, Ru catalyst |
| Abstract | Catalytic asymmetric transfer hydrogenation of aromatic alkyl ketones has been investigated using [Ru(p-cymene)Cl-2](2) and new derivatives of beta-amino alcohols synthesized from (S)-(-)-lactic acid and mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%). Asymmetric transfer hydrogenation of ketones has been investigated using [Ru(p-cymene)Cl-2](2) and beta-amino alcohols synthesized from (S)-(-)-lactic acid and Mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%). |
| DOI | 10.1007/s10562-010-0408-y |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.907 |
Divison category:
Center for Material Characterization (CMC)
Chemical Engineering & Process Development