TY - JOUR T1 - Catalytic asymmetric transfer hydrogenation of ketones using [Ru(p-cymene)Cl-2](2) with chiral amino alcohol ligands JF - Catalysis Letters Y1 - 2010 A1 - Deshpande, Sudhindra H. A1 - Kelkar, Ashutosh A. A1 - Gonnade, Rajesh G. A1 - Shingote, Savita K. A1 - Chaudhari, Raghunath V. KW - Amino alcohol ligand KW - Asymmetric transfer hydrogenation KW - Ketones KW - Ru catalyst AB -

Catalytic asymmetric transfer hydrogenation of aromatic alkyl ketones has been investigated using [Ru(p-cymene)Cl-2](2) and new derivatives of beta-amino alcohols synthesized from (S)-(-)-lactic acid and mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%). Asymmetric transfer hydrogenation of ketones has been investigated using [Ru(p-cymene)Cl-2](2) and beta-amino alcohols synthesized from (S)-(-)-lactic acid and Mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%).

PB - SPRINGER CY - 233 SPRING ST, NEW YORK, NY 10013 USA VL - 138 IS - 3-4 U3 - Foreign U4 - 1.907 ER -