01611nas a2200241 4500008004100000022001400041245012100055210006900176260005700245300001200302490000800314520069700322653002501019653003801044653001201082653001601094100002901110700002501139700002401164700002501188700002901213856012701242 2010 eng d a1011-372X00aCatalytic asymmetric transfer hydrogenation of ketones using [Ru(p-cymene)Cl-2](2) with chiral amino alcohol ligands0 aCatalytic asymmetric transfer hydrogenation of ketones using Rup a233 SPRING ST, NEW YORK, NY 10013 USAbSPRINGERcSEP a231-2380 v1383 a
Catalytic asymmetric transfer hydrogenation of aromatic alkyl ketones has been investigated using [Ru(p-cymene)Cl-2](2) and new derivatives of beta-amino alcohols synthesized from (S)-(-)-lactic acid and mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%). Asymmetric transfer hydrogenation of ketones has been investigated using [Ru(p-cymene)Cl-2](2) and beta-amino alcohols synthesized from (S)-(-)-lactic acid and Mandelic acid as ligands. Chiral secondary alcohols were obtained with good to excellent conversion (60-90%) and moderate to good enantioselectivities (40-86%).
10aAmino alcohol ligand10aAsymmetric transfer hydrogenation10aKetones10aRu catalyst1 aDeshpande, Sudhindra, H.1 aKelkar, Ashutosh, A.1 aGonnade, Rajesh, G.1 aShingote, Savita, K.1 aChaudhari, Raghunath, V. uhttp://library.ncl.res.in/content/catalytic-asymmetric-transfer-hydrogenation-ketones-using-rup-cymenecl-22-chiral-amino-0