Facile synthesis of the spiro-pyridoindolone scaffold via a gold-catalysed intramolecular alkynol cyclisation/hydroindolylation
| Title | Facile synthesis of the spiro-pyridoindolone scaffold via a gold-catalysed intramolecular alkynol cyclisation/hydroindolylation |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | Shinde, MH, V. Ramana, C |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 20 |
| Issue | 10 |
| Pagination | d1ob02483c |
| Date Published | MAR |
| Type of Article | Article |
| ISSN | 1477-0520 |
| Abstract | A simple approach for the synthesis of pyridoindolone scaffolds with a spiroannulated tetrahydrofuran ring is described. The overall process comprises intramolecular sequential gold-catalysed 5-endo-dig alkynol cycloisomerization and subsequent addition of indole C2 to the in situ generated oxocarbenium cation. |
| DOI | 10.1039/d1ob02483c |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.890 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)