%0 Journal Article %J Organic & Biomolecular Chemistry %D 2022 %T Facile synthesis of the spiro-pyridoindolone scaffold via a gold-catalysed intramolecular alkynol cyclisation/hydroindolylation %A Shinde, Mahesh H. %A Ramana, V. Chepuri %X

A simple approach for the synthesis of pyridoindolone scaffolds with a spiroannulated tetrahydrofuran ring is described. The overall process comprises intramolecular sequential gold-catalysed 5-endo-dig alkynol cycloisomerization and subsequent addition of indole C2 to the in situ generated oxocarbenium cation.

%B Organic & Biomolecular Chemistry %V 20 %P d1ob02483c %8 MAR %G eng %N 10 %9 Article %3

Foreign

%4

3.890

%R 10.1039/d1ob02483c