Novel one-pot synthesis of 2-Aryl-4(3H)-quinazolinones using room temperature ionic liquid as reaction medium as well as promoter
| Title | Novel one-pot synthesis of 2-Aryl-4(3H)-quinazolinones using room temperature ionic liquid as reaction medium as well as promoter |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Potewar, TM, Nadaf, RN, Daniel, T, Lahoti, RJ, Srinivasan, KV |
| Journal | Synthetic Communications |
| Volume | 35 |
| Issue | 2 |
| Pagination | 231-241 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 0039-7911 |
| Keywords | 2-amino benzamide, 2-aryl-4(3H)-quinazolinones, benzoyl chlorides, Ionic liquid |
| Abstract | An efficient one-pot synthesis of 2-aryl-4(3H)-quinazolinones from 2-amino benzamides and substituted benzoyl chlorides in a room temperature ionic liquid is described. Compared with the classical reaction conditions, this new synthetic method has the advantages of recyclability of ionic liquid, very good to excellent yields (78-92%), the absence of hazardous and expensive catalysts, and easy workup procedures giving rise to a process with minimum waste. |
| DOI | 10.1081/SCC-200048433 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.065 |
Divison category:
Organic Chemistry