01381nas a2200241 4500008004100000022001400041245013400055210006900189260006800258300001200326490000700338520047000345653002200815653003200837653002200869653001700891100002000908700001800928700001900946700002500965700002300990856012601013 2005 eng d a0039-791100aNovel one-pot synthesis of 2-Aryl-4(3H)-quinazolinones using room temperature ionic liquid as reaction medium as well as promoter0 aNovel onepot synthesis of 2Aryl43Hquinazolinones using room temp a270 MADISON AVE, NEW YORK, NY 10016 USAbMARCEL DEKKER INCcJUL a231-2410 v353 a
An efficient one-pot synthesis of 2-aryl-4(3H)-quinazolinones from 2-amino benzamides and substituted benzoyl chlorides in a room temperature ionic liquid is described. Compared with the classical reaction conditions, this new synthetic method has the advantages of recyclability of ionic liquid, very good to excellent yields (78-92%), the absence of hazardous and expensive catalysts, and easy workup procedures giving rise to a process with minimum waste.
10a2-amino benzamide10a2-aryl-4(3H)-quinazolinones10abenzoyl chlorides10aIonic liquid1 aPotewar, T., M.1 aNadaf, R., N.1 aDaniel, Thomas1 aLahoti, Rajgopal, J.1 aSrinivasan, K., V. uhttp://library.ncl.res.in/content/novel-one-pot-synthesis-2-aryl-43h-quinazolinones-using-room-temperature-ionic-liquid-0