Facile regioselective decomposition of tosylhydrazones: an application towards the synthesis of alpha-lipoic acid
| Title | Facile regioselective decomposition of tosylhydrazones: an application towards the synthesis of alpha-lipoic acid |
| Publication Type | Journal Article |
| Year of Publication | 2005 |
| Authors | Chavan, SP, Kale, RR, Pasupathy, K |
| Journal | Synlett |
| Issue | 7 |
| Pagination | 1129-1132 |
| Date Published | MAY |
| Type of Article | Article |
| ISSN | 0936-5214 |
| Keywords | alpha-lipoic acid, Olefins, Regioselectivity, tosylhydrazones |
| Abstract | A facile regioselective decomposition of tosylhydrazones using NaOH as a base in refluxing isopropyl alcohol is described. This finding has been Successfully applied towards the synthesis of (±)-α-lipoic acid (1). |
| DOI | 10.1055/s-2005-865217 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.323 |
Divison category:
Organic Chemistry