%0 Journal Article %J Synlett %D 2005 %T Facile regioselective decomposition of tosylhydrazones: an application towards the synthesis of alpha-lipoic acid %A Chavan, Subhash P. %A Kale, R. R. %A Pasupathy, K. %K alpha-lipoic acid %K Olefins %K Regioselectivity %K tosylhydrazones %X

A facile regioselective decomposition of tosylhydrazones using NaOH as a base in refluxing isopropyl alcohol is described. This finding has been Successfully applied towards the synthesis of (±)-α-lipoic acid (1).

%B Synlett %I GEORG THIEME VERLAG KG %C RUDIGERSTR 14, D-70469 STUTTGART, GERMANY %P 1129-1132 %8 MAY %G eng %N 7 %9 Article %3 Foreign %4 2.323 %R 10.1055/s-2005-865217