From insertion to multicomponent coupling: temperature dependent reactions of arynes with aliphatic alcohols
| Title | From insertion to multicomponent coupling: temperature dependent reactions of arynes with aliphatic alcohols |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Thangaraj, M, Bhojgude, SSuresh, Mane, MV, Biju, AT |
| Journal | Chemical Communications |
| Volume | 52 |
| Issue | 8 |
| Pagination | 1665-1668 |
| Date Published | NOV |
| ISSN | 1359-7345 |
| Abstract | The temperature dependent selectivity switch in the reaction of arynes with aliphatic alcohols in THF has been reported. At -20 degrees C, arynes smoothly insert into the O-H bond of alcohols to form alkyl aryl ethers. Interestingly, at 60 degrees C, a highly selective multicomponent coupling occurs with the solvent THF acting as the nucleophilic trigger affording (4-(alkoxy)butoxy)arenes. |
| DOI | 10.1039/c5cc08307a |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Organic Chemistry