TY - JOUR T1 - From insertion to multicomponent coupling: temperature dependent reactions of arynes with aliphatic alcohols JF - Chemical Communications Y1 - 2016 A1 - Thangaraj, Manikandan A1 - Bhojgude, Sachin Suresh A1 - Mane, Manoj V. A1 - Biju, Akkattu T. AB -

The temperature dependent selectivity switch in the reaction of arynes with aliphatic alcohols in THF has been reported. At -20 degrees C, arynes smoothly insert into the O-H bond of alcohols to form alkyl aryl ethers. Interestingly, at 60 degrees C, a highly selective multicomponent coupling occurs with the solvent THF acting as the nucleophilic trigger affording (4-(alkoxy)butoxy)arenes.

PB - ROYAL SOC CHEMISTRY CY - THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND VL - 52 IS - 8 U3 -

Foreign

U4 - 6.567 ER -