Synthesis of central spiro-bis-THF fragments of symbiospirols A-C
| Title | Synthesis of central spiro-bis-THF fragments of symbiospirols A-C |
| Publication Type | Journal Article |
| Year of Publication | 2022 |
| Authors | Shinde, MH, Kona, CN, V. Ramana, C |
| Journal | New Journal of Chemistry |
| Volume | 46 |
| Issue | 28 |
| Pagination | 13738-13744 |
| Date Published | JUL |
| Type of Article | Article |
| ISSN | 1144-0546 |
| Abstract | The gold catalysed alkynediol spiroketalization to assemble the central spiro-bis-THF fragments (C22-C33 and C36-C47) of symbiospirols A-C is documented. The adopted chiral pool approach employed commercially available d-glucose and l-malic acid in the synthesis of key building blocks. In addition, two other possible diastereomers have been synthesized in order to establish the relative stereochemistry of the unassigned THF-center of symbiospirols B/C. |
| DOI | 10.1039/d2nj02227c |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.925 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)