Short enantioselective synthesis of guggultetrol, a naturally occurring lipid
| Title | Short enantioselective synthesis of guggultetrol, a naturally occurring lipid |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | George, S, Suryavanshi, G, Sudalai, A |
| Journal | Tetrahedron-Asymmetry |
| Volume | 21 |
| Issue | 5 |
| Pagination | 558-561 |
| Date Published | MAR |
| ISSN | 0957-4166 |
| Abstract | An enantioselective synthesis of the naturally occurring lipid, guggultetrol, is described with an overall yield of 24% starting from commercially available 1-pentadecanol in ten linear steps. The key chiral-inducing steps include a Sharpless asymmetric epoxidation of allylic alcohol and a dihydroxylation of an alpha,beta-unsaturated ester. (C) 2010 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetasy.2010.02.019 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.484 |
Divison category:
Chemical Engineering & Process Development