TY - JOUR T1 - Short enantioselective synthesis of guggultetrol, a naturally occurring lipid JF - Tetrahedron-Asymmetry Y1 - 2010 A1 - George, Shyla A1 - Suryavanshi, Gurunath A1 - Sudalai, Arumugam AB -

An enantioselective synthesis of the naturally occurring lipid, guggultetrol, is described with an overall yield of 24% starting from commercially available 1-pentadecanol in ten linear steps. The key chiral-inducing steps include a Sharpless asymmetric epoxidation of allylic alcohol and a dihydroxylation of an alpha,beta-unsaturated ester. (C) 2010 Elsevier Ltd. All rights reserved.

PB - PERGAMON-ELSEVIER SCIENCE LTD CY - THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND VL - 21 IS - 5 U3 - Foreign U4 - 2.484 ER -