Process development for crystalline xylitol production from corncob biomass by Pichia caribbica
Title | Process development for crystalline xylitol production from corncob biomass by Pichia caribbica |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Dasgupta, D, Sidana, A, Sarkar, B, More, S, Ghosh, D, Bhaskar, T, Ray, A |
Journal | Food and Bioproducts Processing |
Volume | 133 |
Pagination | 45-56 |
Date Published | MAY |
Type of Article | Article |
ISSN | 0960-3085 |
Keywords | Biomass, Corncob, Detoxification, Fermentation, Toxicity analysis, xylitol |
Abstract | Xylitol, a commodity chemical, is widely used in nutraceutical and pharmaceutical formulations. Microbial xylitol production is a promising alternative to mitigate current industrial practice issues and offers an environment-friendly sustainable conversion route. This study demonstrates a bioprocess for xylitol production from corncob using a mesophilic yeast Pichia caribbica. Corncob was hydrolyzed by dilute acid and steam explosion to recover fermentable xylose and used as the feed for xylitol production. Activated carbon treatment (3% w/v) completely removed the biomass-derived inhibitors furfural and hydroxymethyl furfural from the liquid hydrolysate. The fermenting yeast Pichia caribbica produced 124.1 +/- 0.45 g/L xylitol from the detoxified and concentrated corncob hydrolysate with a high yield of 0.80 +/- 0.02 g/g. The crystallized xylitol with 96.5% purity demonstrated no harmful effects on the cell line used as a control for the in-vitro toxicity studies. This proof of concept can be applied to help scale up for bio-refinery-based large-scale production of xylitol from corncob biomass.(c) 2022 Institution of Chemical Engineers. Published by Elsevier Ltd. All rights reserved. |
DOI | 10.1016/j.fbp.2022.02.006 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 5.105 |
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