Process development for crystalline xylitol production from corncob biomass by Pichia caribbica

TitleProcess development for crystalline xylitol production from corncob biomass by Pichia caribbica
Publication TypeJournal Article
Year of Publication2022
AuthorsDasgupta, D, Sidana, A, Sarkar, B, More, S, Ghosh, D, Bhaskar, T, Ray, A
JournalFood and Bioproducts Processing
Volume133
Pagination45-56
Date PublishedMAY
Type of ArticleArticle
ISSN0960-3085
KeywordsBiomass, Corncob, Detoxification, Fermentation, Toxicity analysis, xylitol
Abstract

Xylitol, a commodity chemical, is widely used in nutraceutical and pharmaceutical formulations. Microbial xylitol production is a promising alternative to mitigate current industrial practice issues and offers an environment-friendly sustainable conversion route. This study demonstrates a bioprocess for xylitol production from corncob using a mesophilic yeast Pichia caribbica. Corncob was hydrolyzed by dilute acid and steam explosion to recover fermentable xylose and used as the feed for xylitol production. Activated carbon treatment (3% w/v) completely removed the biomass-derived inhibitors furfural and hydroxymethyl furfural from the liquid hydrolysate. The fermenting yeast Pichia caribbica produced 124.1 +/- 0.45 g/L xylitol from the detoxified and concentrated corncob hydrolysate with a high yield of 0.80 +/- 0.02 g/g. The crystallized xylitol with 96.5% purity demonstrated no harmful effects on the cell line used as a control for the in-vitro toxicity studies. This proof of concept can be applied to help scale up for bio-refinery-based large-scale production of xylitol from corncob biomass.(c) 2022 Institution of Chemical Engineers. Published by Elsevier Ltd. All rights reserved.

DOI10.1016/j.fbp.2022.02.006
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

5.105

Divison category: 
Biochemical Sciences
Database: 
Web of Science (WoS)

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