Novel one-pot synthesis of 2-Aryl-4(3H)-quinazolinones using room temperature ionic liquid as reaction medium as well as promoter

TitleNovel one-pot synthesis of 2-Aryl-4(3H)-quinazolinones using room temperature ionic liquid as reaction medium as well as promoter
Publication TypeJournal Article
Year of Publication2005
AuthorsPotewar, TM, Nadaf, RN, Daniel, T, Lahoti, RJ, Srinivasan, KV
JournalSynthetic Communications
Volume35
Issue2
Pagination231-241
Date PublishedJUL
Type of ArticleArticle
ISSN0039-7911
Keywords2-amino benzamide, 2-aryl-4(3H)-quinazolinones, benzoyl chlorides, Ionic liquid
Abstract

An efficient one-pot synthesis of 2-aryl-4(3H)-quinazolinones from 2-amino benzamides and substituted benzoyl chlorides in a room temperature ionic liquid is described. Compared with the classical reaction conditions, this new synthetic method has the advantages of recyclability of ionic liquid, very good to excellent yields (78-92%), the absence of hazardous and expensive catalysts, and easy workup procedures giving rise to a process with minimum waste.

DOI10.1081/SCC-200048433
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)1.065
Divison category: 
Organic Chemistry