Engineering cell surface glycans with carbohydrate enantiomers to alter bacterial binding and adhesion
| Title | Engineering cell surface glycans with carbohydrate enantiomers to alter bacterial binding and adhesion |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Gade, M, Chaudhary, PMadhukar, Thulasiram, HV, Kikkeri, R |
| Journal | Chemistryselect |
| Volume | 2 |
| Issue | 28 |
| Pagination | 8865-8869 |
| Date Published | SEP |
| Type of Article | Article |
| ISSN | 2365-6549 |
| Keywords | Bioorthogonal reaction, Carbohydrate, E. coli, Enantiomer, Surfaces functionalization |
| Abstract | Chirality of carbohydrate has critical functions in many biological processes. Changes in the configuration of even one sugar molecules may cause abnormal behavior or even inhibit specific processes. Herein, we have shown bioorthogonal conjugation of mannose enantiomers on HeLa cell surfaces induced a different rate of bacterial binding and cell adhesion. |
| DOI | 10.1002/slct.201701875 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.505 |
Divison category:
Organic Chemistry
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