Concise enantioselective synthesis of (+)-lentiginosine

TitleConcise enantioselective synthesis of (+)-lentiginosine
Publication TypeJournal Article
Year of Publication2009
AuthorsShaikh, TMahamadali, Sudalai, A
JournalTetrahedron-Asymmetry
Volume20
Issue19
Pagination2287-2292
Date PublishedOCT
ISSN0957-4166
Abstract

A high yielding enantioselective synthesis of the indolizidine alkaloid, (+)-lentiginosine, has been described based on asymmetric oza-Cope rearrangement and the L-proline catalyzed alpha-aminooxylation of aldehydes. The strategy also makes use of ring-closing metathesis for the construction of piperidine core. (C) 2009 Elsevier Ltd. All rights reserved.

DOI10.1016/j.tetasy.2009.08.027
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)2.484
Divison category: 
Chemical Engineering & Process Development