00967nas a2200157 4500008004100000022001400041245006000055210005600115260010600171300001400277490000700291520036800298100003200666700002200698856008900720 2009 eng d a0957-416600aConcise enantioselective synthesis of (+)-lentiginosine0 aConcise enantioselective synthesis of lentiginosine aTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLANDbPERGAMON-ELSEVIER SCIENCE LTDcOCT a2287-22920 v203 a
A high yielding enantioselective synthesis of the indolizidine alkaloid, (+)-lentiginosine, has been described based on asymmetric oza-Cope rearrangement and the L-proline catalyzed alpha-aminooxylation of aldehydes. The strategy also makes use of ring-closing metathesis for the construction of piperidine core. (C) 2009 Elsevier Ltd. All rights reserved.
1 aShaikh, Tanveer, Mahamadali1 aSudalai, Arumugam uhttp://library.ncl.res.in/content/concise-enantioselective-synthesis-lentiginosine-0