Asymmetric transfer hydrogenation of imines in water/methanol co-solvent system and mechanistic investigation by DFT study
| Title | Asymmetric transfer hydrogenation of imines in water/methanol co-solvent system and mechanistic investigation by DFT study |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Shende, VS, Shingote, SK, Deshpande, SH, Kuriakose, N, Vanka, K, Kelkar, AA |
| Journal | RSC Advances |
| Volume | 4 |
| Issue | 86 |
| Pagination | 46351-46356 |
| Date Published | SEP |
| Type of Article | Article |
| ISSN | 2046-2069 |
| Abstract | Asymmetric transfer hydrogenation of various cyclic imines proceeded efficiently with water/methanol co-solvent media in 20 min with excellent yields and enantioselectivities by employing Rh-TsDPEN catalyst and sodium formate as a hydrogen donor. The role of the co-solvent in enhanced productivity of the reaction was investigated by DFT. The mechanism for ATH of the imines has been discussed on the basis of the DFT study. |
| DOI | 10.1039/c4ra07964g |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.289 |
Divison category:
Chemical Engineering & Process Development