2-Amino-5-methylene-pyrimidine-4,6-dione-based Janus G-C nucleobase as a versatile building block for self-assembly

Title2-Amino-5-methylene-pyrimidine-4,6-dione-based Janus G-C nucleobase as a versatile building block for self-assembly
Publication TypeJournal Article
Year of Publication2023
AuthorsWagh, MA, Shinde, DR, Gamidi, RKrishna, Sanjayan, GJ
JournalOrganic and biomolecular chemistry
Date Published AUG
Type of ArticleArticle; Early Access
ISSN1477-0520
KeywordsDNA Triplex, Peptide nucleic acid, Polymers
Abstract

This communication reports a nature-inspired Janus G-C nucleobase featuring two recognition sites: DDA (G mimic) and DAA (C mimic), which is capable of forming a linear tape-like supramolecular polymer structure. As demonstrated herein, the amino group of this self-assembling system can be further modified to yield a highly stable quadruple H-bonding system as well as a masked self-assembling system cleavable upon exposure to light.

DOI10.1039/d3ob01174g
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.2

Divison category: 
Organic Chemistry
Database: 
Web of Science (WoS)

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