Cyclopropane containing triterpenoids, cycloartenone, and cycloartenol: isolation, chemical transformations, and anticancer studies
| Title | Cyclopropane containing triterpenoids, cycloartenone, and cycloartenol: isolation, chemical transformations, and anticancer studies |
| Publication Type | Journal Article |
| Year of Publication | 2025 |
| Authors | Paul, S, Mandal, K, Santra, MK, Bhattacharya, AK |
| Journal | ChemistrySelect |
| Volume | 10 |
| Issue | 9 |
| Pagination | e202403698 |
| Date Published | MAR |
| Type of Article | Article |
| ISSN | 2365-6549 |
| Keywords | Anticancer studies, Artocarpus heterophyllus, Chemical transformations, Cycloartenol, Cycloartenone |
| Abstract | Cycloartenone and cycloartenol, two plant-derived triterpenoids possessing cyclopropane ring were isolated from the latex of Artocarpus heterophyllus (jackfruit). Cycloartenol was chemically modified to synthesize dihydrocycloartenol via acetylation and deacetylation methodology followed by hydrogenation. Hydroxyl group present in the cycloartenol was also employed for the nitro benzoate formation. All the isolated and synthesized compounds were assayed against MCF7 breast cancer cell line for their anticancer properties. |
| DOI | 10.1002/slct.202403698 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.9 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)
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