`Turning on' to glutathione: a rhodamine-based fluorescent chemodosimeter with nanomolar sensitivity
| Title | `Turning on' to glutathione: a rhodamine-based fluorescent chemodosimeter with nanomolar sensitivity |
| Publication Type | Journal Article |
| Year of Publication | 2024 |
| Authors | Badekar, PS, Deo, HS, Varma, ME, Kulkarni, PP, Maibam, A, Krishnamurty, S, Kumbhar, AA |
| Journal | ChemistrySelect |
| Volume | 9 |
| Issue | 37 |
| Pagination | e202402943 |
| Date Published | OCT |
| Type of Article | Article |
| ISSN | 2365-6549 |
| Keywords | Chemodosimeter, Fluorescence turn-on, GSH, MCF-7 cells, Rhodamine |
| Abstract | A new colorimetric and fluorescence turn-on chemodosimeter for selective detection of GSH over Cys and Hcy with 34-fold enhancement in emission intensity is reported. Probe 1 exhibited ultra-sensitivity toward GSH with 0.125 nM detection limit and successfully displayed GSH detection in MCF-7 live cells. The mechanism of sensing is established by density functional theoretical calculations. |
| DOI | 10.1002/slct.202402943 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.1 |
Divison category:
Physical and Materials Chemistry
Database:
Web of Science (WoS)