`Turning on' to glutathione: a rhodamine-based fluorescent chemodosimeter with nanomolar sensitivity

Title`Turning on' to glutathione: a rhodamine-based fluorescent chemodosimeter with nanomolar sensitivity
Publication TypeJournal Article
Year of Publication2024
AuthorsBadekar, PS, Deo, HS, Varma, ME, Kulkarni, PP, Maibam, A, Krishnamurty, S, Kumbhar, AA
JournalChemistrySelect
Volume9
Issue37
Paginatione202402943
Date PublishedOCT
Type of ArticleArticle
ISSN2365-6549
KeywordsChemodosimeter, Fluorescence turn-on, GSH, MCF-7 cells, Rhodamine
Abstract

A new colorimetric and fluorescence turn-on chemodosimeter for selective detection of GSH over Cys and Hcy with 34-fold enhancement in emission intensity is reported. Probe 1 exhibited ultra-sensitivity toward GSH with 0.125 nM detection limit and successfully displayed GSH detection in MCF-7 live cells. The mechanism of sensing is established by density functional theoretical calculations.

DOI10.1002/slct.202402943
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

2.1

Divison category: 
Physical and Materials Chemistry
Database: 
Web of Science (WoS)

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