Bacteriophages: status quo and emerging trends toward one health approach
Title | Bacteriophages: status quo and emerging trends toward one health approach |
Publication Type | Journal Article |
Year of Publication | 2024 |
Authors | Samson, R, Dharne, M, Khairnar, K |
Journal | Science of The Total Environment |
Volume | 908 |
Date Published | JAN |
Type of Article | Review |
ISSN | 0048-9697 |
Keywords | Antimicrobial resistance (AMR), Bacteriophages, One-health, Therapeutics commercialization |
Abstract | The alarming rise in antimicrobial resistance (AMR) among the drug-resistant pathogens has been attributed to the ESKAPEE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, Enterobacter sp., and Escherichia coli). Recently, these AMR microbes have become difficult to treat, as they have rendered the existing therapeutics ineffective. Thus, there is an urgent need for effective alternatives to lessen or eliminate the current infections and limit the spread of emerging diseases under the ``One Health'' framework. Bacteriophages (phages) are naturally occurring biological resources with extraordinary potential for biomedical, agriculture/food safety, environmental protection, and energy production. Specific unique properties of phages, such as their bactericidal activity, host specificity, potency, and biocompatibility, make them desirable candidates in therapeutics. The recent biotechnological advancement has broadened the repertoire of phage applications in nanoscience, material science, physical chemistry, and soft |
DOI | 10.1016/j.scitotenv.2023.168461 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 9.8 |
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