Radical cascade cyclization of unactivated alkene-tethered indoles with aryldiazonium salt and sodium metabisulfite to access Azo- and Sulfonylated-2,3-Dihyro-1H-pyrrolo[1,2-a]indoles
| Title | Radical cascade cyclization of unactivated alkene-tethered indoles with aryldiazonium salt and sodium metabisulfite to access Azo- and Sulfonylated-2,3-Dihyro-1H-pyrrolo[1,2-a]indoles |
| Publication Type | Journal Article |
| Year of Publication | 2023 |
| Authors | Kumar, P, Rai, A, Kumar, M, Krishna, GRama, Das, U |
| Journal | Journal of Organic Chemistry |
| Volume | 88 |
| Issue | 13 |
| Pagination | 9123-9129 |
| Date Published | JUN |
| Type of Article | Article |
| ISSN | 0022-3263 |
| Abstract | A method for the construction ofheterocyclic scaffold2,3-dihyro-1H-pyrrolo[1,2-a]indolesvia arylsulfonylradical-triggered cascade cyclization of unactivated alkene-tetheredindoles in the absence of any external photocatalyst has been developed.This protocol features easily accessible starting materials such assodium metabisulfite and aryldiazonium tetrafluoroborates at roomtemperature and offers good functional group compatibility, enablingthe introduction of various functionalized sulfonyl and azo groupsinto pyrrolo[1,2-a]indoles. |
| DOI | 10.1021/acs.joc.3c00759 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.6 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)
Add new comment