Ready access to densely substituted furans using Tsuji-Wacker type cyclization
Title | Ready access to densely substituted furans using Tsuji-Wacker type cyclization |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Masal, DP, Choudhury, R, Singh, A, D. Reddy, S |
Journal | Journal of Organic Chemistry |
Volume | 87 |
Issue | 1 |
Pagination | 556-568 |
Date Published | JAN |
Type of Article | Article |
ISSN | 0022-3263 |
Abstract | A competent method for the construction of highly substituted furans catalyzed by Pd(II) and Cu(II) chloride has been developed. The method provides easy access to di-, tri-, and tetrasubstituted furans from corresponding diols with relatively mild conditions in a unified strategy. The developed method has been successfully tested with more than 25 substrates, which resulted in furans of multiple substitution patterns with up to 84% isolated yields. |
DOI | 10.1021/acs.joc.1c02567 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 4.198 |
Divison category:
Organic Chemistry
Database:
Web of Science (WoS)
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