Direct oxidation of bromo-derived Fischer-Borsche oxo-ring using molecular iodine with combined experimental and computational study

TitleDirect oxidation of bromo-derived Fischer-Borsche oxo-ring using molecular iodine with combined experimental and computational study
Publication TypeJournal Article
Year of Publication2022
AuthorsHumne, VT, Ghom, MH, Naykode, MS, Dangat, Y, Vanka, K, Lokhande, P
JournalOrganic & Biomolecular Chemistry
Volume20
Issue29
Pagination5726-5729
Date PublishedJUL
Type of ArticleArticle
ISSN1477-0520
Abstract

A direct oxidation of the bromo-derived Fischer-Borsche oxo-ring leading to carbazolequinone has been developed by using molecular iodine. This unprecedented transformation has been used for the modular synthesis of the anti-cardiotonic agent murrayaquinone. Furthermore, the present method has been generalized to a broad range of functional groups, with good to excellent yield.

DOI10.1039/d2ob00793b
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.890

Divison category: 
Physical and Materials Chemistry
Database: 
Web of Science (WoS)

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