Plasma-derived extracellular vesicles reveal galectin-3 binding protein as potential biomarker for early detection of glioma

TitlePlasma-derived extracellular vesicles reveal galectin-3 binding protein as potential biomarker for early detection of glioma
Publication TypeJournal Article
Year of Publication2021
AuthorsRana, R, Chauhan, K, Gautam, P, Kulkarni, M, Banarjee, R, Chugh, P, Chhabra, SSingh, Acharya, R, Kalra, SKumar, Gupta, A, Jain, S, Ganguly, NKumar
JournalFrontiers in Oncology
Volume11
Pagination778754
Date PublishedNOV 26
Type of ArticleArticle
ISSN2234-943X
Keywordsblood-based biomarker, early detection, galectin-3 binding protein, plasma-derived extracellular vesicles, proteomics
Abstract{Gliomas are the most common type of the malignant brain tumor, which arise from glial cells. They make up about 40% of all primary brain tumors and around 70% of all primary malignant brain tumors. They can occur anywhere in the central nervous system (CNS) and have a poor prognosis. The average survival of glioma patients is approximately 6-15 months with poor aspects of life. In this edge, identification of proteins secreted by cancer cells is of special interest because it may provide a better understanding of tumor progression and provide early diagnosis of the diseases. Extracellular vesicles (EVs) were isolated from pooled plasma of healthy controls (n=03) and patients with different grades of glioma (Grade I or II or III
DOI10.3389/fonc.2021.778754
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)6.244
Divison category: 
Biochemical Sciences

Add new comment