Separation of a diastereomeric diol pair using the mechanical properties of crystals
| Title | Separation of a diastereomeric diol pair using the mechanical properties of crystals |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Gamidi, RKrishna, Dandawate, M, Choudhury, R, Tothadi, S, Nangia, A, D. Reddy, S |
| Journal | Crystengcomm |
| Volume | 23 |
| Issue | 40 |
| Pagination | 7056-7060 |
| Date Published | OCT |
| Type of Article | Article |
| Abstract | We report the separation of a (2S,3R/S)-3-ethyl-1-phenylhex-5-ene-2,3-diol (ephd) diastereomeric pair with visually indistinguishable acicular morphologies based on their mechanical responses, which is found to be more efficient than conventional separation methods. Furthermore, the molecular crystals of (2S,3R)-ephd show elastic deformation, while (2S,3S)-ephd fractures in a brittle manner under similar conditions. |
| DOI | 10.1039/d1ce01055g |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.545 |
Divison category:
Organic Chemistry
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