Three in one: triple G-C-T base-coded brahma nucleobase amino acid: synthesis, peptide formation, and structural features

TitleThree in one: triple G-C-T base-coded brahma nucleobase amino acid: synthesis, peptide formation, and structural features
Publication TypeJournal Article
Year of Publication2021
AuthorsWagh, MA, Maity, R, Bhosale, RJ, Semwal, D, Tothadi, S, Vaidhyanathan, R, Sanjayan, GJ
JournalJournal of Organic Chemistry
Volume86
Issue21
Pagination15689-15694
Date PublishedNOV
Type of ArticleArticle
ISSN0022-3263
AbstractThis note reports the synthesis and peptide formation of a novel triple G-C-T nucleobase amino acid (NBA) building block featuring three recognition faces: DDA (G mimic), DAA (C mimic), and ADA (T mimic). Readily obtainable in multigram scale in a remarkably easy one-step reaction, this unique NBA building block offers scope for wide ranging applications for nucleic acid recognition and nucleic acid peptide/protein interaction studies.
DOI10.1021/acs.joc.1c01228
Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)4.354
Divison category: 
Organic Chemistry

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