Synthesis of artemisinin derived glycoconjugates inspired by click chemistry

TitleSynthesis of artemisinin derived glycoconjugates inspired by click chemistry
Publication TypeJournal Article
Year of Publication2019
AuthorsGoswami, L, Paul, S, Kotammagari, TK, Bhattacharya, AK
JournalNew Journal of Chemistry
Volume43
Issue10
Pagination4017-4021
Date PublishedMAR
Type of ArticleArticle
ISSN1144-0546
Abstract

Herein we describe the synthesis of artemisinin based glycoconjugates (9a-i) through employing a Cu(i)-catalysed reaction between -propargylated dihydroartemisinin (7a) and azido sugars (8a-i), with moderate to excellent yields. Our synthesized artemisinin based glycoconjugates (9a-i) could prove to be an interesting class of bioactive molecules, suitable for the study of their various biological activities.

DOI10.1039/c8nj05737k
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.069

Divison category: 
Organic Chemistry

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