Tf2NH catalyzed 1,6-conjugate addition of 2-hydroxy-p-quinone methides with -functionalized ketones: access to 2,3,4,9-Tetrahydro-1H-xanthenones and 4H-Chromene Derivatives

TitleTf2NH catalyzed 1,6-conjugate addition of 2-hydroxy-p-quinone methides with -functionalized ketones: access to 2,3,4,9-Tetrahydro-1H-xanthenones and 4H-Chromene Derivatives
Publication TypeJournal Article
Year of Publication2019
AuthorsSatbhaiya, S, Khonde, NS, Rathod, J, Gonnade, R, Kumar, P
JournalEuropean Journal of Organic Chemistry
Issue20
Pagination3127-3133
Date PublishedJUN
Type of ArticleArticle
ISSN1434-193X
Keywords-Functionalized ketone, 1, 6-Conjugated addition, Bronsted acid, Chromenes, Xanthenones
Abstract

A Bronsted acid catalyzed tandem 1,6-conjugate sequential cycloaddition reaction using 2-hydroxy-p-quinone methides and -functionalized ketones is reported. The method allows xanthenones and chromenes to be accessed in moderate to excellent yield with broad substrate scope, which could be further functionalized to give a versatile set of products.

DOI10.1002/ejoc.201900370
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

3.029

Divison category: 
Organic Chemistry
Physical and Materials Chemistry

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