Fluorogenic BODIPY molecular rotor as an apoptosis marker

TitleFluorogenic BODIPY molecular rotor as an apoptosis marker
Publication TypeJournal Article
Year of Publication2019
AuthorsAshokkumar, P, Ashoka, AHoskere, Collot, M, Das, A, Klymchenko, AS
JournalChemical Communications
Volume55
Issue48
Pagination6902-6905
Date PublishedJUN
Type of ArticleArticle
ISSN1359-7345
Abstract

Based on a BODIPY molecular rotor and a zinc-dipicolylamine receptor, we designed a fluorogenic probe for the detection of apoptosis. Being poorly emissive in solution and with healthy cells, it selectively binds phosphatidylserine of early apoptotic cells and internalizes into late apoptotic cells, lighting up its green fluorescence.

DOI10.1039/c9cc03242h
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)

6.164

Divison category: 
Organic Chemistry

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