Fluorescent probe for specific detection of cysteine in the lipid dense region of cells

TitleFluorescent probe for specific detection of cysteine in the lipid dense region of cells
Publication TypeJournal Article
Year of Publication2015
AuthorsAli, F, Anila, HA, Taye, N, Gonnade, RG, Chattopadhyay, S, Das, A
JournalChemical Communications
Volume51
Issue95
Pagination16932-16935
Date PublishedSEP
Type of ArticleArticle
ISSN1359-7345
Abstract

A new cysteine (Cys) specific chemodosimetric reagent (ER-F) is used in imaging of endogenous Cys localized in the lipid dense region of the live Hct116 cells and the release of Cys within HepG2 cells from a drug following a biochemical transformation. A silica surface, modified with ER-F, could be used for quantitative estimation of Cys present in aqueous solution (pH 7.2) and in a human blood plasma (HBP).

DOI10.1039/c5cc07450a
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)6.567
Divison category: 
Organic Chemistry

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