Nickel-catalyzed N-vinylation of heteroaromatic amines via C-H bond activation
| Title | Nickel-catalyzed N-vinylation of heteroaromatic amines via C-H bond activation |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Landge, VG, Rana, J, Subaramanian, M, Balaraman, E |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 15 |
| Issue | 33 |
| Pagination | 6896-6900 |
| Date Published | SEP |
| Type of Article | Article |
| ISSN | 1477-0520 |
| Keywords | Alkylation, Amination Reactions, Anilines, Aryl Chlorides, halides, Monoarylation, O Bonds, Precatalyst, Pyrimidines, Removeble Directing Group |
| Abstract | Here, we report a ligand- and reductant-free nickel-catalyzed N-vinylation of heteroaromatic amines using biorenewable p-cymene as a solvent. This unprecedented cross-coupling strategy has high functional group tolerance (halides, alkoxy, cyano, chiral motif, etc.) and proceeded via C-H bond activation. |
| DOI | 10.1039/c7ob01791j |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.559 |
Divison category:
Catalysis and Inorganic Chemistry
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