Efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion
| Title | Efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Mujahid, M, Mujumdar, P, Sasikumar, M, Deshmukh, SP, Muthukrishnan, M |
| Journal | Tetrahedron-Asymmetry |
| Volume | 28 |
| Issue | 7 |
| Pagination | 983-986 |
| Date Published | JUL |
| Type of Article | Article |
| Abstract | A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (> 99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described. (C) 2017 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetasy.2017.06.001 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.108 |
Divison category:
Organic Chemistry