Catalytic enantioselective aza-piancatelli rearrangement
| Title | Catalytic enantioselective aza-piancatelli rearrangement |
| Publication Type | Journal Article |
| Year of Publication | 2017 |
| Authors | Gade, AB, Patil, NT |
| Journal | Synlett |
| Volume | 28 |
| Issue | 9 |
| Pagination | 1096-1100 |
| Date Published | JUN |
| Type of Article | Article |
| Abstract | The design and development of an enantioselective aza-Piancatelli rearrangement reaction are described. In the presence of a chiral phosphoric acid catalyst, furylcarbinols react with anilines to afford highly functionalized cyclopentenones with excellent diastereo-and enantioselectivities. The process was shown to be scalable, and up to 1 gram of starting material could be employed under mild reaction conditions. |
| DOI | 10.1055/s-0036-1558952 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.323 |
Divison category:
Organic Chemistry