Synthesis of cyclic peptides using a palladium-catalyzed enyne cycloisomerization
| Title | Synthesis of cyclic peptides using a palladium-catalyzed enyne cycloisomerization |
| Publication Type | Journal Article |
| Year of Publication | 2006 |
| Authors | Balraju, V, R. Dev, V, D. Reddy, S, Iqbal, J |
| Journal | Tetrahedron Letters |
| Volume | 47 |
| Issue | 21 |
| Pagination | 3569-3571 |
| Date Published | MAY |
| Abstract | In this letter, we report a palladium-catalyzed enyne cycloisomerization of linear peptides to generate small cyclic peptides embedded with a conjugated 1,3-diene. The utility of these resulting macrocyclic dienes is demonstrated by carrying out [4+2] cycloadditions with dienophiles to generate constrained cyclic peptides with cyclic linkers. (c) 2006 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2006.03.053 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry