Efficient synthesis of varenicline
Title | Efficient synthesis of varenicline |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Pasikanti, S, D. Reddy, S, Venkatesham, B, Dubey, PK, Iqbal, J, Das, P |
Journal | Tetrahedron Letters |
Volume | 51 |
Issue | 1 |
Pagination | 151-152 |
Date Published | JAN |
Abstract | Synthesis of varenicline the antismoking drug has been achieved in six steps with 10% overall yield. A Diels-Alder reaction, oxidative cleavage of an olefin and reductive amination remain as key steps in the synthesis (C) 2009 Elsevier Ltd. All rights reserved. |
DOI | 10.1016/j.tetlet.2009.10.107 |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry