Practical synthesis of phthalimides and benzamides by a multicomponent reaction involving arynes, isocyanides, and CO2/H2O

TitlePractical synthesis of phthalimides and benzamides by a multicomponent reaction involving arynes, isocyanides, and CO2/H2O
Publication TypeJournal Article
Year of Publication2014
AuthorsKaicharla, T, Thangaraj, M, Biju, AT
JournalOrganic Letters
Volume16
Issue6
Pagination1728–1731
Date PublishedMAR
Abstract

Transition-metal-free multicomponent reactions involving arynes and isocyanides with either CO2 or H2O have been reported. With CO2 as the third component, the reactions resulted in the formation of N-substituted phthalimides. The utility of water as the third component furnished benzamide derivatives in moderate to good yields. These reactions took place under mild conditions with broad scope.

DOI10.1021/ol500403x
Funding Agency

Council of Scientific & Industrial Research (CSIR) - India

Type of Journal (Indian or Foreign)Foreign
Impact Factor (IF)7.03
Divison category: 
Organic Chemistry