N-Heterocyclic carbene-catalyzed diastereoselective synthesis of β-lactone-fused cyclopentanes using homoenolate annulation reaction
| Title | N-Heterocyclic carbene-catalyzed diastereoselective synthesis of β-lactone-fused cyclopentanes using homoenolate annulation reaction |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Mukherjee, S, Mondal, S, Patra, A, Gonnade, RG, Biju, AT |
| Journal | Chemical Communications |
| Volume | 51 |
| Issue | 46 |
| Pagination | 9559-9562 |
| Date Published | MAY |
| Abstract | NHC-catalyzed annulation of enals with 2-enoylpyridines or 2-enoylpyridine N-oxides leading to the diastereoselective synthesis of β-lactone-fused cyclopentanes is reported. The reaction proceeds via the generation of homoenolate equivalent intermediates and tolerates a broad range of functional groups. |
| DOI | 10.1039/C5CC02960K |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 6.567 |
Divison category:
Center for Material Characterization (CMC)
Organic Chemistry