Syntheses of 1,2-amino alcohols and their applications for oxazaborolidine catalyzed enantioselective reduction of aromatic ketones
| Title | Syntheses of 1,2-amino alcohols and their applications for oxazaborolidine catalyzed enantioselective reduction of aromatic ketones |
| Publication Type | Journal Article |
| Year of Publication | 2007 |
| Authors | Vatmurge, NS, Hazra, BG, Pore, VS |
| Journal | Australian Journal of Chemistry |
| Volume | 60 |
| Issue | 3 |
| Pagination | 196-204 |
| Date Published | APR |
| Type of Article | Article |
| ISSN | 0004-9425 |
| Abstract | Six new chiral 1,2-amino alcohol derivatives have been synthesized starting from (1R, 2R)-2-amino-1-phenylpropane-1,3- diol. Asymmetric reduction of aryl ketones with in-situ generated oxazaborolidine from these amino alcohol derivatives and BH3 center dot Me2S afforded secondary alcohols with good yield and moderate to high enantiomeric excess. |
| DOI | 10.1071/CH06412 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 1.427 |
Divison category:
Organic Chemistry