Physicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles

TitlePhysicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles
Publication TypeJournal Article
Year of Publication2016
AuthorsOsifeko, OL, Uddin, I, Mashazi, PN, Nyokong, T
JournalNew Journal of Chemistry
Volume40
Issue3
Pagination2710-2721
Date PublishedJAN
ISSN1144-0546
Abstract

An AB(3) type photosensitiser, consisting of 4-pyridylsulfanyl units (denoted as B-3) and one aminophenoxy (denoted as A) group (complex 3) was synthesized. Complex 3 was then quaternized to form complex 4. The aminophenoxy substituent of complex 3 was used for the formation of the amide linkage with the carboxylic functionalised magnetic nanoparticles. Complexes 3 and 4 and their conjugates with magnetic nanoparticles were then used for photodynamic antimicrobial chemotherapy on E. coli. The cationic photosensitiser 4 showed a high efficiency for photodynamic antimicrobial chemotherapy at a very low concentration compared to its conjugate on E. coli.

DOI10.1039/c5nj01922b
Type of Journal (Indian or Foreign)

Foreign

Impact Factor (IF)3.277
Divison category: 
Biochemical Sciences