Physicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles
Title | Physicochemical and antimicrobial photodynamic chemotherapy of unsymmetrical indium phthalocyanines alone or in the presence of magnetic nanoparticles |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Osifeko, OL, Uddin, I, Mashazi, PN, Nyokong, T |
Journal | New Journal of Chemistry |
Volume | 40 |
Issue | 3 |
Pagination | 2710-2721 |
Date Published | JAN |
ISSN | 1144-0546 |
Abstract | An AB(3) type photosensitiser, consisting of 4-pyridylsulfanyl units (denoted as B-3) and one aminophenoxy (denoted as A) group (complex 3) was synthesized. Complex 3 was then quaternized to form complex 4. The aminophenoxy substituent of complex 3 was used for the formation of the amide linkage with the carboxylic functionalised magnetic nanoparticles. Complexes 3 and 4 and their conjugates with magnetic nanoparticles were then used for photodynamic antimicrobial chemotherapy on E. coli. The cationic photosensitiser 4 showed a high efficiency for photodynamic antimicrobial chemotherapy at a very low concentration compared to its conjugate on E. coli. |
DOI | 10.1039/c5nj01922b |
Type of Journal (Indian or Foreign) | Foreign |
Impact Factor (IF) | 3.277 |
Divison category:
Biochemical Sciences