Total synthesis of (-)-(6R,11R,14S)-colletallol via proline catalyzed alpha-aminoxylation and Yamaguchi macrolactonization
| Title | Total synthesis of (-)-(6R,11R,14S)-colletallol via proline catalyzed alpha-aminoxylation and Yamaguchi macrolactonization |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Kauloorkar, SVandana, Kumar, P |
| Journal | RSC Advances |
| Volume | 6 |
| Issue | 68 |
| Pagination | 63607-63612 |
| Date Published | JUN |
| ISSN | 2046-2069 |
| Abstract | A simple and efficient synthesis of the 14-membered macrolide (-)-(6R,11R,14S)-colletallol was achieved in a highly diastereoselective manner with high overall yield. The stereogenic centre was generated using a proline catalyzed alpha-aminoxylation reaction and the ring was constructed using Yamaguchi protocol. |
| DOI | 10.1039/c6ra08484b |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 3.289 |
Divison category:
Organic Chemistry