Multi-gram scale synthesis of hunanamycin A, an antibiotic natural product from the marine source
| Title | Multi-gram scale synthesis of hunanamycin A, an antibiotic natural product from the marine source |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Shingare, RD, Farhana, SAda, D. Reddy, S |
| Journal | Tetrahedron Letters |
| Volume | 57 |
| Issue | 32 |
| Pagination | 3662-3663 |
| Date Published | AUG |
| ISSN | 0040-4039 |
| Keywords | Antibacterial, Biomimetic synthesis, Gram scale synthesis, Natural product, Riboflavin |
| Abstract | A simple, practical, and biomimetic approach to access antibiotic natural product hunanamycin A starting from readily available inexpensive material Riboflavin is disclosed here. The present synthesis consists of three operationally simple, protecting group free steps and it is far superior when compared with the previous route. Using this route one can make multi-gram quantities of the natural product which will help in further biological assays, in particular exploring the potential of treating food infections. (C) 2016 Elsevier Ltd. All rights reserved. |
| DOI | 10.1016/j.tetlet.2016.07.003 |
| Type of Journal (Indian or Foreign) | Foreign |
| Impact Factor (IF) | 2.347 |
Divison category:
Organic Chemistry